HORDB

General Information

ID: hor002537
Uniprot ID: NA
Protein name: NGIWYamide
Gene name: NA
Organism: Stichopus japonicus
Family: NA
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: NA
GO MF: NA
GO BP: NA
GO CC: NA

Sequence Information

Sequence: NGIWY
Length: 5
Propeptide: NA
Signal peptide: NA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Activity

Function: Cause muscle contraction or modulate electrically-induced muscle contraction
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure

Disulfide bond: NA
Structure ID: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002537_AF2.pdb

hor002537_ESM.pdb

Physical Information

Mass:	72325	Formula:	C32H41N7O8
Absent amino acids:	ACDEFHKLMPQRSTV	Common amino acids:	GINWY
pI:	6.09	Basic residues:	0
Polar residues:	3	Hydrophobic residues:	2
Hydrophobicity:	-32	Boman Index:	141
Half-Life:	1.4 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	78
Instability Index:	-3904	Extinction Coefficient cystines:	6990
Absorbance 280nm:	1747.5

Literature

PubMed ID: 22952987
Title: The Protein Precursors of Peptides That Affect the Mechanics of Connective Tissue and/or Muscle in the Echinoderm Apostichopus Japonicus